rabbit as an animal model for experimental research

Rabbit is the most commonly used animal species in intravitreal pharmacokinetics, but it has been criticized as being a poor model of human eye. The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. Rabbit as an animal model for experimental research. Rabbit as an animal model for experimental research. Animal experimentation is carried out in consultation with the veterinary wing but it is essential that be familiar with experimental protocols of animal model to be able to design an approriate study. However, information on precautions when using this animal as an experimental model is limited. This is more so in place where the veterinary facilities are not easily available.Span Rabbits are commonly used as subjects for screening implant material. Manjeet Mapara, 1 Betsy Sara Thomas, 2 and K. M. Bhat 2 ... experimentation is carried out in consultation with the veterinary wing but it is essential that be familiar with experimental protocols of animal model to be able to design an approriate study. The critique is based on some anatomical differences, properties of the vitreous humor, and observed differences in drug concentrations in the anterior chamber after intravitreal injections. ... experimentation is carried out in consultation with the veterinary wing but it is essential that be familiar with experimental protocols of animal model to be able to design an approriate study. Eye Research and Ocular Cancer Key advantages to using rabbits as experimental models for ophthalmic research are the size of the rabbit eye, a large body of accumulated data on the anatomy and physiology of the rabbit eye, and most importantly its similarity to the human eye (Gwon 2008). In fact, rabbit was the first animal model used for studying human atherosclerosis, more than a century ago.